Imaging biomarkers of posttraumatic epileptogenesis
نویسندگان
چکیده
منابع مشابه
Preparing undercut model of posttraumatic epileptogenesis in rodents.
Partially isolated cortex ("undercut") is an animal model of posttraumatic epileptogenesis. The surgical procedure involves cutting through the sensorimotor cortex and the underneath white matter (undercut) so that a specific region of the cerebral cortex is largely isolated from the neighboring cortex and subcortical regions(1-3). After a latency of two or more weeks following the surgery, epi...
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Partially isolated cortical islands prepared in vivo become epileptogenic within weeks of the injury. In this model of chronic epileptogenesis, recordings from cortical slices cut through the injured area and maintained in vitro often show evoked, long- and variable-latency multiphasic epileptiform field potentials that also can occur spontaneously. These events are initiated in layer V and are...
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ژورنال
عنوان ژورنال: Epilepsia
سال: 2019
ISSN: 0013-9580,1528-1167
DOI: 10.1111/epi.16357